Al Shargi H.M. Investigation of statistical characteristics of biomolecules: in view of current epigenetic developments (Saarbrucken, 2010). - ОГЛАВЛЕНИЕ / CONTENTS
Навигация

Архив выставки новых поступлений | Отечественные поступления | Иностранные поступления | Сиглы
ОбложкаAl Shargi H.M. Investigation of statistical characteristics of biomolecules: in view of current epigenetic developments. - Saarbrücken: VDM Verlag Dr. Müller, 2010. - 116 p.: ill. - Ref.: p.105-116. - ISBN 978-3-639-23674-3
 

Место хранения: 021 | Институт цитологии и генетики CO РАН | Новосибирск | Библиотека

Оглавление / Contents
 
Table of Contents ............................................... 3
List of Tables .................................................. 5
List of Figures and Illustrations ............................... 6

CHAPTER ONE: INTRODUCTION ....................................... 9
1.1  Introduction ............................................... 9
1.2  Problem Description ........................................ 9
1.3  Life Sciences Foundation .................................. 11
     1.3.1  The Double Helix and the Sequence Hypothesis ....... 11
     1.3.2  The Human Genome Project ........................... 12
     1.3.3  Computational Biology and System Biology ........... 13
1.4  Biological Definitions and Terminology .................... 15
     1.4.1  Basic Definitions .................................. 15
     1.4.2  The DNA Molecule ................................... 17
     1.4.3  The Central Dogma .................................. 18
     1.4.4  The Genetic Code and the Proteins .................. 22
1.5  Information Theoretical Entropy ........................... 25
     1.5.1  Information Contents and Redundancy ................ 31
     1.5.2  Shannon's Statistical Language Models .............. 33
     1.5.3  Information Theory and Biological Sequences ........ 36
1.6  Holography ................................................ 37
     1.6.1  Operational Principle .............................. 37
     1.6.2  The Concept of Holographic Universe ................ 38
     1.6.3  The Holographic Theory of the Brain ................ 45

CHAPTER TWO: STRUCTURAL CHARACTERIZATION OF BIOMOLECULES
AND ITS IMPLICATION ............................................ 48
2.1  Information Deficiency of DNA ............................. 48
     2.1.1  Law of Requisite Variety ........................... 50
     2.1.2  Biology's Enigmas .................................. 52
     2.1.3  Alternative Splicing ............................... 54
     2.1.4  Active Role of DNA ................................. 55
2.2  Information Theoretical Analysis of DNA Sequences ......... 57
     2.2.1  Incompressibility of DNA sequences ................. 58
     2.2.2  Structural Redundancies in Proteins ................ 61
2.3  Entropy Transformation along the Protein Synthesis
     Path ...................................................... 62
2.4  Analysis of Epigenetic Influences on Organism 
     Development ............................................... 67
     2.4.1  Epigenetic Mechanism ............................... 67
     2.4.2  Epigenetic Inheritance and the Memory Problem ...... 70
     2.4.3  Biological Complexity and Entangled Life ........... 73

CHAPTER THREE: BIOLOGICAL INFORMATION PROCESSING AS CLOUD
COMPUTING ...................................................... 75
3.1  The Emerging Cloud Computing Paradigm ..................... 75
3.2  A Cloud Computing Model for Biological Information
     Processing ................................................ 77
3.3  Interactive feedbacks in the organization of the
     holographic Universe ...................................... 79
3.4  Hypothesized Properties of Biomolecules and the
     Operational Significance of their Structure ............... 88
3.5  Possible detecting of absolute orientation with respect
     to the holographic reference beam ......................... 93
     3.5.1  Testing the effects on radioactive decay rate ...... 94
     3.5.2  Testing the effects on stem cell lineage
            commitment ......................................... 95
     3.5.3  Testing of the effects of prion folding ............ 97
            3.5.3.1  Prion Disease Contradiction to the 
                     Central Dogma ............................. 97
            3.5.3.2  Prion Proteins as Entangled Molecules ..... 99

CHAPTER FOUR: CONCLUSION ...................................... 101

REFERENCES .................................................... 105


Архив выставки новых поступлений | Отечественные поступления | Иностранные поступления | Сиглы
 

[О библиотеке | Академгородок | Новости | Выставки | Ресурсы | Библиография | Партнеры | ИнфоЛоция | Поиск]
  Пожелания и письма: branch@gpntbsib.ru
© 1997-2024 Отделение ГПНТБ СО РАН (Новосибирск)
Статистика доступов: архив | текущая статистика
 

Документ изменен: Wed Feb 27 14:23:32 2019 Размер: 7,769 bytes.
Посещение N 1454 c 22.05.2012