Polyamines: methods and protocols / ed. by A.E.Pegg, R.A.Casero (Jr.). - New York: Humana Press; Springer, 2011. - xiv, 524 p.: ill. - (Methods in molecular biology; 720) (Springer protocols). - Bibliogr. at the end of articles. - Ind.: p.519-523. - ISBN 978-1-61779-033-1; ISSN 1064-3745  Место хранения:   021 | Институт цитологии и генетики CO РАН | Новосибирск | Библиотека

Оглавление / Contents

Preface ......................................................... v Contributors ................................................... xi Part I Introduction 1 Current Status of the Polyamine Research Field ............... 3 Anthony E. Pegg and Robert A. Casero, Jr. Part II Identification of Polyamine Metabolic Enzymes and Characterization of Polyamine-Regulated Genes and Ion Channels 2 Exploring Polyamine Biosynthetic Diversity Through Comparative and Functional Genomics ......................... 39 Anthony J. Michael 3 Characterization of Genes for Polyamine Modulon ............. 51 Kazuei Igarashi and Keiko Kashiwagi 4 Posttranscriptional Regulation of Gene Expression in Epithelial Cells by Polyamines .............................. 67 Lan Xiao and Jian-Ying Wang 5 Identification, Chemical Synthesis, and Biological Functions of Unusual Polyamines Produced by Extreme Thermophiles ................................................ 81 Tairo Oshima, Toshiyuki Moriya, and Tusuke Terui 6 Polyamine Block of Inwardly Rectifying Potassium Channels ................................................... 113 Harley T. Kurata, Wayland W.L. Cheng, and Colin G. Nichols Part III Transgenic Models for Study of Polyamine Function 7 Carcinogenesis Studies in Mice with Genetically Engineered Alterations in Polyamine Metabolism ............. 129 David J. Feith 8 Transgenic Rodents with Altered SSAT Expression as Models of Pancreatitis and Altered Glucose and Lipid Metabolism ... 143 Anne Uimari, Mervi T. Hyvönen, Eija Pirinen, and Leena Alhonen 9 Use of (Gyro) Gy and Spermine Synthase Transgenic Mice to Study Functions of Spermine ............................. 159 Xiaojing Wang and Anthony E. Pegg Part IV Enzymes Involved in Polyamine Catabolism and posttranslational protein modification 10 A Simple Assay for Mammalian Spermine Oxidase: A Polyamine Catabolic Enzyme Implicated in Drug Response and Disease ................................................ 173 Andrew C. Goodwin, Tracy R. Murray-Stewart, and Robert A. Casero, Jr. 11 Characterization, Assay, and Substrate Specificity of Plant Polyamine Oxidases ................................... 183 Panagiotis N. Moschou and Kalliopi A. Roubelakis- Angelakis 12 Assay of Deoxyhypusine Synthase Activity ................... 195 Edith C. Wolff, Seung Bum Lee, and Myung Нее Park 13 Assay of Deoxyhypusine Hydroxylase Activity ................ 207 Jong Hwan Park, Edith C. Wolff, and Myung Нее Park Part V Regulation of Polyamine Content 14 Identification and Assay of Allosteric Regulators of S-Adenosylmethionine Decarboxylase ......................... 219 Erin K. Willert, Lisa N. Kinch, and Margaret A. Phillips 15 Protocols for Studying Antizyme Expression and Function .... 237 Noriyuki Murai, Yasuko Murakami, and Senya Matsufuji 16 Identification, Assay, and Functional Analysis of the Antizyme Inhibitor Family .................................. 269 Chaim Kahana 17 Posttranscriptional Regulation of Ornithine Decarboxylase .............................................. 279 Shannon L. Nowotarski, Sofia Origanti, and Lisa M. Shantz Part VI Polyamine Transport and Uptake 18 Identification and Assays of Polyamine Transport Systems in Escherichia coli and Saccharomyces cerevisiae ........... 295 Keiko Kashiwagi and Kazuei Igarashi 19 Genetic and Biochemical Analysis of Protozoal Polyamine Transporters ............................................... 309 Marie-Pierre Hasne and Buddy Ullman 20 Heparan Sulfate Proteoglycan-Mediated Polyamine Uptake ..... 327 Johanna Welch, Katrin Svensson, Paulina Kucharzewska, and Mattias Belting 21 Polyamine Transport Systems in Mammalian Cells and Tissues .................................................... 339 Takeshi Uemura and Eugene W. Gerner 22 Procedures to Evaluate the Importance of Dietary Polyamines ................................................. 349 Paul Acheampong, Mary J. Macleod, and Heather M. Wallace Part VII Polyamines and Disease 23 Determination of N1,N12-Diacetylspermine in Urine: A Novel Tumor Marker ....................................... 367 Masao Kawakita, Kyoko Hiramatsu, Mari Yanagiya, Yosuke Doi, and Mieko Kosaka 24 Spermidine/Spermine-N1-Acetyltransferase in Kidney Ischemia Reperfusion Injury ................................ 379 Kamyar Zahedi and Manoocher Soleimani 25 Use of Polyamine Metabolites as Markers for Stroke and Renal Failure .............................................. 395 Kazuei Igarashi and Keiko Kashiwagi 26 Methods to Evaluate Alterations in Polyamine Metabolism Caused by Helicobacter pylori Infection .................... 409 Alain P. Gobert, Rupesh Chaturvedi, and Keith T. Wilson 27 High-Resolution Capillary Gas Chromatography in Combination with Mass Spectrometry for Quantification of Three Major Polyamines in Postmortem Brain Cortex ....... 427 Gary Gang Chen, Laura M. Fiori, Orval A. Mamer, and Gustavo Turecki 28 Spermine Synthase Deficiency Resulting in X-Linked Intellectual Disability (Snyder-Robinson Syndrome) ......... 437 Charles E. Schwartz, Xaiojing Wang, Roger E. Stevenson, and Anthony E. Pegg Part VIII Chemistry and Analysis 29 Methylated Polyamines as Research Tools .................... 449 Alex R. Khomutov, Janne Weisell, Maxim A. Khomutov, Nikolay A. Grigorenko, Alina R. Simonian, Merja R. Häkkinen, Tuomo A. Keinänen, Mervi T. Hyvönen, Leena Alhonen, Sergey N. Kochetkov, and Jouko Vepsäläinen 30 Fluorescent Substrates for Polyamine Catabolic Enzymes and Transport .............................................. 463 Koichi Takao and Akira Shirahata 31 Use of Polyamine Derivatives as Selective Histone Deacetylase Inhibitors ..................................... 475 Patrick M. Woster 32 Measurement of Polyamine pK Values ......................... 493 Ian S. Blagbrough, Abdelkader A. Metwally, and Andrew J. Geall 33 Polyamine Analysis by LC-MS ................................ 505 Merja R. Häkkinen Index ......................................................... 519