RNA infrastructure and networks (New York; Austin, 2011). - ОГЛАВЛЕНИЕ / CONTENTS
Навигация

Архив выставки новых поступлений | Отечественные поступления | Иностранные поступления | Сиглы
ОбложкаRNA infrastructure and networks / ed. by L.J.Collins. - New York: Springer Science+Business Media; Austin: Landes Bioscience, 2011. - xxi, 280 p.: ill. - (Advances in experimental medicine and biology; vol.722). - Incl. bibl. ref. - Ind.: p.275-280. - ISBN 978-1-4614-0331-9
 

Оглавление / Contents
 
1  THE RNA INFRASTRUCTURE: AN INTRODUCTION TO ncRNA NETWORKS .... 1
   Lesley J. Collins
   Abstract ..................................................... 1
   Introduction ................................................. 1
   RNAs Processing Other RNAs ................................... 2
   Spatial Regulation of Eukaryotic RNA Processing .............. 7
   RNA Regulation, Connecting Components of the RNA-
   Infrastructure ............................................... 9
   Conclusion .................................................. 15

2  RNA INTERACTIONS ............................................ 20
   Manja Marz and Peter F. Stadler
   Abstract .................................................... 20
   Introduction ................................................ 20
   ncRNA-DNA Interactions ...................................... 21
   RNA-RNA Interactions ........................................ 23
   ncRNA-Protein Interactions .................................. 31
   Conclusion .................................................. 33

3  PLANT RNA SILENCING IN VIRAL DEFENCE ........................ 39
   Vitantonio Pantaleo
   Abstract .................................................... 39
   Introduction ................................................ 39
   Generation of Viral Small Interfering RNAs: Viruses, 
   vsiRNAs and Dicers .......................................... 40
   Post-Dicing Modification of vsiRNAs ......................... 47
   Antiviral Effector Complexes ................................ 47
   Amplification and Spread of Antiviral Defence ............... 49
   Movement of Antiviral Silencing ............................. 51
   Viral Suppressors of RNA Silencing .......................... 52
   Conclusion .................................................. 53

4  MicroRNAS AS POST-TRANSCRIPTIONAL MACHINES AND THEIR
   INTERPLAY WITH CELLULAR NETWORKS ............................ 59
   Sarath Chandra Janga and Swathi Vallabhaneni
   Abstract	.................................................... 59
   Introduction ................................................ 60
   Biogenesis, Genomic Organization and Evolution of miRNAs .... 61
   Methods to Identify miRNAs and Their Targets ................ 63
   MicroRNA Interplay with Other Cellular Networks ............. 65
   Expression Dynamics and Crosstalk of miRNAs with Other
   Regulatory Factors .......................................... 69
   Conclusion .................................................. 70

5  SPATIOTEMPORAL ASPECTS OF MicroRNA-MEDIATED GENE
   REGULATION .................................................. 75
   Joris Pothof and Dik C. van Gent
   Abstract	.................................................... 75
   Introduction ................................................ 75
   DNA Damage Response as an Example of Multilayered
   Regulation .................................................. 77
   MicroRNA-Mediated Gene Silencing in the DDR ................. 78
   Mechanism of Fast MicroRNA Regulation ....................... 81
   Localization of the MicroRNA-Mediated Gene Silencing
   Machinery ................................................... 82
   Conclusion .................................................. 84

6  SPLICEOSOMAL RNA INFRASTRUCTURE: THE NETWORK OF SPLICING
   COMPONENTS AND THEIR REGULATION BY miRNAS ................... 86
   Lesley J. Collins
   Abstract .................................................... 86
   Introduction ................................................ 86
   The Spliceosome as an Example of the RNA-Infrastructure ..... 87
   RNA-Protein Interaction Networks ............................ 89
   Regulatory (Expression Modulated) Networks .................. 93
   Spatiotemporal Dynamic RNA Networks ......................... 98
   Conclusion ................................................. 100

7  CONSTRUCTION, STRUCTURE AND DYNAMICS OF POST-
   TRANSCRIPTIONAL REGULATORY NETWORK DIRECTED BY RNA-
   BINDING PROTEINS ........................................... 103
   Sarath Chandra Janga and Nitish Mittal
   Abstract ................................................... 103
   Introduction ............................................... 104
   RNA Binding Proteins and Post-Transcriptional Regulation ... 104
   Methods to Identify RBPs and Their Targets ................. 107
   RBPs and Post-Transcriptional Operons ...................... 109
   Post-Transcriptional Network Formed by RBPs ................ 110
   Expression Dynamics of RBPs in Post-Transcriptional 
   Networks ................................................... 112
   Conclusion ................................................. 114

8  SAFE KEEPING THE MESSAGE: mRNP COMPLEXES TWEAKING AFTER
   TRANSCRIPTION .............................................. 118
   Said Hafidh, Věra Čapková and David Honys
   Abstract ................................................... 118
   Introduction ............................................... 119
   RNP-Infrastructure; Post-Transcriptional Modulator of 
   Gene Expression ............................................ 119
   Pre-mRNA Processing and the Initiation of mRNP Formation ... 122
   Mobilization to the Site of Storage and niRNA 
   Localization ............................................... 125
   Cytoskeleton: Actin and Microtubule Dynamics as 
   a Floating Raft for mRNPs Subcellular Localization ......... 126
   Intra- and Intercellular Translocation of mRNPs ............ 126
   Storage of mRNPs and mRNA Turnover ......................... 127
   Systematic Translation Repression by Small RNAs ............ 131
   Reinitiating Translation of the Localized, 
   Translationally Sequestered mRNAs .......................... 132
   Conclusion ................................................. 133

9  UNEXPECTED FUNCTIONS OF tRNA AND tRNA PROCESSING ENZYMES ... 137
   Rebecca L. Hurto
   Abstract ................................................... 137
   Introduction ............................................... 137
   tRNAs and Transcription .................................... 138
   tRNA Fragments ............................................. 140
   Aminoacyl-tRNA Functions Beyond Translation ................ 147
   tRNA Processing Enzymes Affect More Than tRNA .............. 148
   Aminoacyl-tRNA Synthetases, tRNA and Disease ............... 149
   Conclusion ................................................. 151

10 PROGRAMMED DNA ELIMINATION IN TETRAHYMENA: A SMALL RNA-
   MEDIATED GENOME SURVEILLANCE MECHANISM ..................... 156
   Kensuke Kataoka and Kazufumi Mochizuki   
   Abstract ................................................... 156
   Introduction ............................................... 157
   Nuclear Dimorphism in Tetrahymena .......................... 159
   Epigenetic Regulation of DNA Elimination by Small RNAS ..... 163
   Biogenesis of scnRNA ....................................... 163
   scnRNA Selection ........................................... 165
   scnRNA-Induced Heterochromatin Formation and DNA
   Elimination ................................................ 166
   Evolutionary Considerations ................................ 167
   Future Prospects ........................................... 169
   Conclusion ................................................. 170
   
11 LONG NONCODING RNA AND EPIGENOMICS ......................... 174
   Chandrasekhar Kanduri
   Abstract ................................................... 174
   Introduction ............................................... 174
   Long ncRNAs and Tumor Suppressor Genes ..................... 176
   Long ncRNAs and Homeobox Genes ............................. 177
   Long ncRNAs and Dosage Compensation ........................ 179
   Long ncRNAs and Pluripotency ............................... 184
   Long ncRNAs and Genomic Imprinting ......................... 186
   Long ncRNAs and Centromeric Heterochromatin ................ 189
   Conclusion ................................................. 191

12 PROMOTER-ASSOCIATED LONG NONCODING RNAs REPRESS 
   TRANSCRIPTION THROUGH A RNA BINDING PROTEIN TLS ............ 196
   Riki Kurokawa
   Abstract ................................................... 196
   Introduction ............................................... 197
   The Target RNA Sequences Recognized by TLS ................. 197
   Domain Structure of TLS .................................... 200
   Transcription-Regulatory Long ncRNA, Cyclin Dl pncRNA ...... 203
   Conclusion ................................................. 206

13 RNA NETWORKS IN PROKARYOTES I: CRISPRs AND RIBOSWITCHES .... 209
   Patrick J. Biggs and Lesley J. Collins
   Abstract ................................................... 209
   Introduction ............................................... 209
   Riboswitches Control Gene and Operon Expression Via
   Metabolite Binding ......................................... 210
   The CRISPR/Cas System is Analogous, but Not Homologous,
   to Eukaryotic RNAi ......................................... 213
   Conclusion ................................................. 218

14 RNA NETWORKS IN PROKARYOTES II: tRNA PROCESSING AND SMALL
   RNAs ....................................................... 221
   Lesley J. Collins and Patrick J. Biggs
   Abstract	................................................... 221
   Introduction ............................................... 221
   RNase P and tRNA Processing in Bacteria and Archaea ........ 222
   Bacterial Small RNAs and Sigma Factors ..................... 224
   Transfer Messenger RNA V ................................... 227
   Conclusion ................................................. 228

15 LOCALIZATION OF THE BACTERIAL RNA INFRASTRUCTURE 
   Kenneth C. Keiler
   Abstract ................................................... 231
   Introduction ............................................... 231
   Localized Transcription and mRNA ........................... 232
   Spatial Control of RNA Degradation and Processing .......... 233
   EF-Tu is a Component of the Cytoskeleton ................... 235
   Localization of Trans-Translation Components ............... 235
   Spatial Control of Gene Expression ......................... 236
   Conclusion ................................................. 236

16 SMALL RNA DISCOVERY AND CHARACTERISATION IN EUKARYOTES
   USING HIGH-THROUGHPUT APPROACHES ........................... 239
   Helio Pais, Simon Moxon, Tamas Dalmay and Vincent Moulton   
   Abstract ................................................... 239
   Introduction ............................................... 239
   The Mechanisms of RNA Silencing ............................ 240
   Using Microarrays and DNA Sequencing to Measure RNA ........ 243
   High-Throughput Approaches for the Discovery and
   Functional Classification of sRNAs ......................... 244
   Conclusion ................................................. 250

17 HOW OLD ARE RNA NETWORKS? .................................. 255
   Toni Daly, X. Sylvia Chen and David Penny   
   Abstract ................................................... 255
   Introduction ............................................... 255
   Regulatory Networks of Small RNAs .......................... 256
   RNA Regulation and Defence Against the Dark Arts ........... 259
   Other Regulatory RNAs ...................................... 266
   How Old are the Different Interactions of RNA? ............. 267
   Conclusion ................................................. 269

INDEX ......................................................... 275


Архив выставки новых поступлений | Отечественные поступления | Иностранные поступления | Сиглы
 

[О библиотеке | Академгородок | Новости | Выставки | Ресурсы | Библиография | Партнеры | ИнфоЛоция | Поиск]
  Пожелания и письма: branch@gpntbsib.ru
© 1997-2024 Отделение ГПНТБ СО РАН (Новосибирск)
Статистика доступов: архив | текущая статистика
 

Документ изменен: Wed Feb 27 14:23:54 2019. Размер: 15,802 bytes.
Посещение N 1572 c 25.09.2012