Functioning of transmembrane receptors in cell signaling / editors-in-chief: R.A.Bradshaw, E.A.Dennis. - San Diego: Academic Press, 2011. - xvi, 442 p.: ill. (some col.). - Bibliogr. at the end of the chapters. - Ind.: p.427-442. - ISBN 978-0-12-382211-6  Место хранения:   056 | Институт химической биологии и фундаментальной медицины CO РАН | Новосибирск| Библиотека

Оглавление / Contents

Section A - Overview ............................................ 1 1 Transmembrane Receptors and Their Signaling Properties ....... 3 Ralph A. Bradshaw and Edward A. Dennis Section В - Biophysical Principles and General Properties ....... 9 2 Structural and Energetic Basis of Molecular Recognition ..... 11 Emil Alexov and Barry Honig 3 Free Energy Landscapes in Protein-Protein Interactions ...... 15 Jacob Piehler and Gideon Schreiber 4 Molecular Sociology ......................................... 23 Irene M. A. Nooren and Janet M. Thornton 5 FRET Analysis of Signaling Events in Cells .................. 29 Peter J. Verveer and Philippe I.H. Bastiaens 6 Structures of Serine/Threonine and Tyrosine Kinases ......... 35 Stevan R. Hubbard 7 Large-Scale Structural Analysis of Protein Tyrosine Phosphatases ................................................ 41 Alastair J. Barr and Stefan Knapp 8 Transmembrane Receptor Oligomerization ...................... 47 Darren R. Tyson and Ralph A. Bradshaw Section С - Major Receptor Families ............................ 53 Part I Receptor Tyrosine Kinases ...................................... 55 9 Protein Tyrosine Kinase Receptor Signaling Overview ......... 57 Carl-Henrik Heldin 10 Receptor Tyrosine Kinase Signaling and Ubiquitination ....... 65 Daniela Hoeller and Ivan Dikic 11 Insulin Receptor Complex and Signaling by Insulin ........... 69 Lindsay C. Sparrow and S. Lance Macaulay 12 Structure and Mechanism of the Insulin Receptor Tyrosine Kinase ...................................................... 75 Stevan R. Hubbard 13 IRS-Protein Scaffolds and Insulin/IGF Action in Central and Peripheral Tissues ...................................... 83 Morris F. White 14 The Epidermal Growth Factor Receptor Family ................. 95 Wolfgang J. Köstler and Yosef Yarden 15 Epidermal Growth Factor Kinases and their Activation in Receptor Mediated Signaling ................................ 103 Andrew H.A. Clayton 16 Role of Lipid Domains in EGF Receptor Signaling ............ 111 Linda J. Pike 17 Signaling by the Platelet-Derived Growth Factor Receptor Family ..................................................... 117 Lars Rönnstrand 18 The Fibroblast Growth Factor (FGF) Signaling Complex ....... 125 Wallace L. McKeehan, Fen Wang, and Yongde Luo 19 The Mechanism of NGF Signaling Suggested by the p75 and TrkA Receptor Complexes .................................... 133 J. Fernando Bazan and Christian Wiesmann 20 The Mechanism of VEGFR Activation by VEGF .................. 143 Christian Wiesmann 21 Mechanisms and Functions of Eph Receptor signaling ......... 149 Martin Lackmann Part 2 Cytokine Receptors ............................................ 157 22 Overview of Cytokine Receptors ............................. 159 Robert M. Stroud 23 Cytokine Receptor Signaling ................................ 161 Mojib Javadi Javed, Terri D. Richmond, and Dwayne L. Barber 24 Growth Hormone and Prolactin Family of Hormones and Receptors: The Structural Basis for Receptor Activation and Regulation ............................................. 177 Anthony A. Kossiakoff and Charles V. Clevenger 25 Erythropoietin Receptor as a Paradigm for Cytokine Signaling .................................................. 185 Deborah J. Stauber, Minmin Yu, and Ian A. Wilson 26 Structure of IFN4 and its Receptors ........................ 193 Mark R. Walter Part 3 G Protein-Coupled Receptors ................................... 197 27 Structures of Heterotrimeric G Proteins and their Complexes .................................................. 199 Stephen R. Sprang 28 G Protein-Coupled Receptor Structures ...................... 209 Veli-Pekka Jaakola and Raymond C. Stevens 29 Heterotrimeric G-Protein Signaling at Atomic Resolution .... 219 David G. Lambright 30 Structure and Function of G-Protein-Coupled Receptors: Lessons from Recent Crystal Structures ..................... 225 Thomas P. Sakmar 31 Chemokines and Chemokine Receptors: Structure and Function ................................................... 231 Caroly J. Raport and Patrick W. Gray 32 The β2 Adrenergic Receptor as a Model for G-Protein- Coupled Receptor Structure and Activation by Diffusible Hormones ................................................... 237 Daniel M. Rosenbaum, Søren С.F. Rasmussen, and Brian K. Kobilka 33 Agonist-Induced Desensitization and Endocytosis of G-protein-Coupled Receptors ................................ 245 Michael Tanowitz and Mark von Zastrow 34 Functional Role(s) of Dimeric Complexes Formed from G-Protein-Coupled Receptors ................................ 253 Raphael Rozenfeld and Lakshmi A. Devi Part 4 TGFβ Receptors ................................................ 263 35 Receptor-Ligand Recognition in the TGF&beta Superfamily as Suggested by Crystal Structures of their Ectodomain Complexes .................................................. 265 Matthias K. Dreyer 36 TGFЯ Signal Transduction ................................... 273 Cristoforo Silvestri, Rohit Bose, Liliana Attisano, and Jeffrey L. Wrana 37 The Smads .................................................. 285 Malcolm Whitman Part 5 TNF Receptors ................................................. 291 38 Structure and Function of Tumor Necrosis Factor (TNF) at the Cell Surface ........................................... 293 Hao Wu and Sarah G. Hymowitz 39 Tumor Necrosis Factor Receptor-Associated Factors in Immune Receptor Signal Transduction ........................ 305 Qian Yin, Su-Chang Lin, Yu-Chih Lo, Steven M. Damo, and Hao Wu Part 6 Guanylyl Cyclases ............................................. 313 40 Guanylyl Cyclases .......................................... 315 Lincoln R. Potter Section D - Other Transmembrane Signaling Proteins ............ 325 Part I Adhesion Molecules ............................................ 327 41 Mechanistic Features of Cell-Surface Adhesion Receptors .... 329 Steven C. Almo, Anne R. Bresnick, and Xuewu Zhang 42 Structural Basis of Integrin Signaling ..................... 337 Robert C. Liddington 43 Carbohydrate Recognition and Signaling ..................... 341 James M. Rini and Hakon Leffler Part 2 Ion Channels .................................................. 349 44 An Overview of Ion Channel Structure ....................... 351 Daniel L. Minor, Jr. 45 Voltage-Gated Calcium Channels ............................. 359 William A. Catterall 46 Store-Operated Calcium Channels ............................ 373 James W. Putney, Jr. 47 Intracellular Calcium Signaling ............................ 377 Dagmar Harzheim, H. Llewelyn Roderick, and Martin D. Bootman 48 Cyclic Nucleotide-Regulated Cation Channels ................ 383 Martin Biel Part 3 Immunoglobulin Receptors ...................................... 389 49 Immunoglobulin-Fc Receptor Interactions .................... 391 Jenny M. Woof 50 T Cell Receptor/pMHC Complexes ............................. 399 Markus G. Rudolph, Robyn L. Stanfield, and Ian A. Wilson 51 NK Receptors ............................................... 407 Roland K. Strong 52 Toll-Like Receptors-Structure and Signaling ................ 415 Istvan Botos and David R. Davies 53 Toll Family Receptors ...................................... 421 Yann Hyvert and Jean-Luc Imler Index ......................................................... 427