Protein synthesis and translational control: a subject collection from Cold Spring Harbor perspectives in biology / ed. by J.W.B.Hershey, N.Sonenberg, M.B.Mathews. - Cold Spring Harbor: Cold Spring Harbor Laboratory Press, 2012. - vii, 352 p.: ill. - (Cold Spring Harbor perspectives in biology). - Incl. bibl. ref. - Ind.: p.345-352. - ISBN 978-1-936113-46-0  Место хранения:   056 | Институт химической биологии и фундаментальной медицины CO РАН | Новосибирск| Библиотека

Оглавление / Contents

Preface ....................................................... vii Principles of Translational Control: An Overview ................ 1 John W.B. Hershey, Nahum Sonenberg, and Michael B. Mathews The Structure and Function of the Eukaryotic Ribosome .......... 11 Daniel N. Wilson and Jamie H. Doudna Cate The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges ........................................ 29 Alan G. Hinnebusch and Jon R. Lorsch The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes ...................................... 55 Thomas E. Dever and Rachel Green Single-Molecule Analysis of Translational Dynamics ............. 71 Alexey Petrov, Jin Chen, Sean O'Leary, Albert Tsai, and Joseph D. Puglisi The Current Status of Vertebrate Cellular mRNA IRESs ........... 89 Richard J. Jackson From Cis-Regulatory Elements to Complex RNPs and Back ......... 109 Fatima Gebauer, Thomas Preiss, and Matthias W. Hentze Regulation of mRNA Translation by Signaling Pathways .......... 123 Philippe P. Roux and Ivan Topisirovic Protein Secretion and the Endoplasmic Reticulum ............... 147 Adam M. Benham New Insights into Translational Regulation in the Endoplasmic Reticulum Unfolded Protein Response ............... 163 Graham D. Pavitt and David Ron P-Bodies and Stress Granules: Possible Roles in the Control of Translation and mRNA Degradation ........................... 177 Carolyn J. Decker and Roy Parker mRNA Localization and Translational Control in Drosophila Oogenesis ..................................................... 193 Paul Lasko Toward a Genome-Wide Landscape of Translational Control ....... 209 Ola Larsson, Bin Tian, and Nahum Sonenberg Imaging Translation in Single Cells Using Fluorescent Microscopy .................................................... 225 Jeffrey A. Chao, Young J. Yoon, and Robert H. Singer A Molecular Link between miRISCs and Deadenylases Provides New Insight into the Mechanism of Gene Silencing by MicroRNAs .................................................... 237 Joerg E. Braun, Eric Huntzinger, and Elisa Izaurralde Translational Control in Cancer Etiology ...................... 253 Davide Ruggero Cytoplasmic RNA-Binding Proteins and the Control of Complex Brain Function ................................................ 281 Jennifer C. Darnell and Joel D. Richter Tinkering with Translation: Protein Synthesis in Virus- Infected Cells ................................................ 299 Derek Walsh, Michael B. Mathews, and Ian Mohr Emerging Therapeutics Targeting mRNA Translation .............. 327 Abba Malina, John R. Mills, and Jerry Pelletier Index ......................................................... 345