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ОбложкаLundblad R.L. Biotechnology of plasma proteins. - Boca Raton: CRC/Taylor & Francis, 2013. - (Protein science series). - Bibliogr. at the end of the chapters. - Ind.: p.441-446. - ISBN 978-1-4398-5026-8
Шифр: (И/Р26-L96) 02
 

Место хранения: 02 | Отделение ГПНТБ СО РАН | Новосибирск

Оглавление / Contents
 
Preface ........................................................ ix
Acknowledgments ................................................ xi
Author ....................................................... xiii

Chapter 1  Blood, Plasma, Cells, and Other Biological Fluids .... 1
Chapter 2  Plasma Fractionation and Plasma Protein Products .... 19
Chapter 3  Methods for the Analysis of Plasma and Plasma
   Protein Fractions ........................................... 47
Chapter 4  Albumin ............................................. 83
   Structure of Albumin ........................................ 86
   In Vitro Chemical Modification of Albumin .................. 101
   Albumin as a Carrier ....................................... 113
   Ligand-Binding by Albumin .................................. 121
   Purification and Characterization of HSA for Clinical Use .. 123
   Biological Activity of Albumin ............................. 125
   Enzymatic Activity of Albumin .............................. 126
   Clinical Use of Albumin .................................... 129
   Albumin as Diagnostic/Biomarker ............................ 132
   Pharmacokinetics of Albumin ................................ 133
   Analytical Methods for Albumin Including Use of Albumin
   as Standard for Analytical Methods ......................... 134
   Albumin as Excipient ....................................... 136
   Conclusion ................................................. 136
   References ................................................. 136
Chapter 5  Plasma Immunoglobulins ............................. 183
Chapter 6  Factor VIII and von Willebrand Factor .............. 233
   von Willebrand Factor ...................................... 253
   Economic Issues Impacting the Hemophilia Business .......... 255
   Conclusions and Future Directions .......................... 257
   References ................................................. 257
Chapter 7  Plasma Proteinase Inhibitors ....................... 285
   Antithrombin ............................................... 285
   α1,-Antitrypsin (a,-Antiprotease Inhibitor, SERPINA1) ...... 293
   Heparin Cofactor II (SERPIND1) ............................. 301
   α2-Macroglobulin ........................................... 301
   Tissue Factor Pathway Inhibitor ............................ 304
   α2-Antiplasmin ............................................. 311
   C1-Inhibitor (C1-Esterase Inhibitor) ....................... 315
   Plasminogen Activator Inhibitor-1 .......................... 319
   Protein С Inhibitor (Plasminogen Activator Inhibitor-3) .... 322
   References ................................................. 323
Chapter 8  Vitamin K-Dependent Proteins ....................... 367
Chapter 9  Miscellaneous Plasma Proteins ...................... 401
   Fibrinogen ................................................. 401
   Fibrin Sealant ............................................. 402
   Autologous Fibrin Sealant .................................. 408
   Fibrinogen and Tissue Soldering ............................ 408
   Thrombin and Fibrin Foam ................................... 410
   Fibrinogen Plastics ........................................ 411
   Thrombin ................................................... 412
   Plasminogen and Plasmin .................................... 412
   Butyrylcholinesterase ...................................... 415
   Fibronectin ................................................ 415

References .................................................... 417
Index ......................................................... 441

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