71.
(11) Patent number: 2144024
(46) Date of publication: 10.01.2000
(51) Int. Cl.7: C 07 C 279/02, A 61 K 31/155
(21) Application number: 98119896/04
(22) Application date: 28.10.1998
(71) Applicant:
Irkutskij institut khimii SO RAN
(72) Inventor:
Stankevich V.K.,
Kukharev B.F.,
Lopyrev V.A.,
Klimenko G.R.,
Belozerov L.E.,
Antonik L.M.,
Shelupaev A.P.,
Kolesnikov S.I.,
Barkova N.P.
(73) Proprietor:
Irkutskij institut khimii SO RAN
(98) Mail address:
664033, Irkutsk, ul.Favorskogo 1, IrIKh SO RAN, otdel mezhdunarodnykh svjazej i patentno-litsenzionnoj rabot
(54) METHOD OF PREPARING POLYHEXAMETHYLENE GUANIDINE
(57)
FIELD: chemical industry. SUBSTANCE: described is method of preparing polymethylene guanidine by condensation of guanidine carbonate with hexamethylene diamine followed by treatment with polyhexamethylene guanidine carbonate with orthophosporic acid. Condensation of guanidine carbonate and hexamethylene diamine is carried out at temperature of 110-165 C in solvent having restricted solubility with respect to polyhexamethylene guanidine and carbonated thereof. EFFECT: higher bacteriostatic activity of the desired product. 4 ex, 1 tbl
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