Anticancer agents from natural products
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Anticancer agents from natural products / ed. by Cragg G.M., Kingston D.G.I., Newman D.J. - Boca Raton: Taylor & Francis/CRC Press, 2005. - 577 p. - ISBN 0-8493-1863-7.
 
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 Chapter 1 Introduction ....................................................... 1
 Gordon M. Cragg, David G.I. Kingston, and David J. Newman

 Chapter 2 Camptothecin and Its Analogs ....................................... 5
 Nicolas J. Rahier, Craig J. Thomas, and Sidney M. Hecht

 Chapter 3 The Discovery and Development of the Combretastatins .............. 23
 Kevin G. Pinney, Christopher Jelinek, Klaus Edvardsen, David J. Chaplin,
 and George R. Pettit

 Chapter 4 Homoharringtonine and Related Compounds ........................... 47
 Hideji Itokawa, Xihong Wang, and Kuo-Hsiung Lee

 Chapter 5 Podophyllotoxins and Analogs ...................................... 71
 Kuo-Hsiung Lee and Zhiyan Xiao

 Chapter 6 Taxol and Its Analogs ............................................. 89
 David G.I. Kingston

 Chapter 7 The Vinca Alkaloids .............................................. 123
 Francoise Gueritte and Jacques Fahy

 Chapter 8 The Bryostatins .................................................. 137
 David J. Newman

 Chapter 9 The Isolation, Characterization, and Development of a Novel
           Class of Potent Antimitotic Macrocyclic Depsipeptides:
           The Cryptophycins ................................................ 151
 Rima S. Al-awar and Chuan Shih

 Chapter 10 Chemistry and Biology of the Discodermolides, Potent Mitotic
            Spindle Poisons ................................................. 171
 Sarath P. Gunasekera and Amy E. Wright

 Chapter 11 The Dolastatins: Novel Antitumor Agents from Dolabella
            auricularia ..................................................... 191
 Erik Flahive and Jayaram Srirangam

 Chapter 12 Ecteinascidin 743 (ET-743; YondelisTM), Aplidin, and
            Kahalalide F .................................................... 215
 Ruben Henriquez, Glynn Faircloth, and Carmen Cuevas

 Chapter 13 Discovery of E7389, a Fully Synthetic Macrocyclic Ketone
            Analog of Halichondrin B ........................................ 241
 Melvin J. Yu, Yoshito Kishi, and Bruce A. Littlefield

 Chapter 14 HTI-286, A Synthetic Analog of the Antimitotic Natural Product
            Hemiasterlin .................................................... 267
 Raymond J. Andersen and Michel Roberge

 Chapter 15 The Actinomycins ................................................ 281
 Anthony B. Mauger and Helmut Lackner

 Chapter 16 Anthracyclines .................................................. 299
 Federico Maria Arcamone

 Chapter 17 Ansamitocins (Maytansinoids) .................................... 321
 Tin-Wein Yu and Heinz G. Floss

 Chapter 18 Benzoquinone Ansamycins ......................................... 339
 Kenneth M. Snader

 Chapter 19 Bleomycin Group Antitumor Agents ................................ 357
 Sidney M. Hecht

 Chapter 20 Biochemical and Biological Evaluation of (+)-CC-1065 Analogs
            and Conjugates with Polyamides .................................. 383
 Rohtash Kumar and J.William Lown

 Chapter 21 Epothilone, a Myxobacterial Metabolite with Promising
            Antitumor Activity .............................................. 413
 Gerhard Hofle and Hans Reichenbach

 Chapter 22 Enediynes ....................................................... 451
 Philip R. Hamann, Janis Upeslacis, and Donald B. Borders

 Chapter 23 The Mitomycins .................................................. 475
 William A. Remers

 Chapter 24 Staurosporines and Structurally Related Indolocarbazoles as
            Antitumor Agents ................................................ 499
 Michelle Prudhomme

 Chapter 25 Combinatorial Biosynthesis of Anticancer Natural Products ....... 519
 Michael G. Thomas, Kathryn A. Bixby, and Ben Shen

 Chapter 26 Developments and Future Trends in Anticancer Natural Products
            Drug Discovery .................................................. 553
 David J. Newman and Gordon M. Cragg

 Index ...................................................................... 573


Вверх Anticancer agents from natural products / ed. by Cragg G.M., Kingston D.G.I., Newman D.J. - Boca Raton: Taylor & Francis/CRC Press, 2005. - 577 p. - ISBN 0-8493-1863-7.

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